Digital innovation is a fundamental driver of the digital transformation, leading to radical changes in the ways people interact, create, produce and consume. Digital innovation not only gives rise to new and novel products and services, but it also creates opportunities for new business models and markets, and it can drive efficiencies in the public sector and beyond. Moreover, digital transformation is reshaping all stages of science, from agenda setting, to experimentation, knowledge sharing and public engagement. Digital technologies and data also drive innovation in a wide range of sectors, including education, health, finance, insurance, transportation, energy, agriculture, fisheries and manufacturing, as well as the ICT sector itself.